and specificity for proteinase 3 (PR3-ANCA), and the other with perinuclear fluorescence pattern (P-ANCA) with myeloperoxidase specificity (MPO-ANCA)—account for this association and both are ...

Three patients relapsed (after 12, 16, and 24 months, respectively) following elevated ANCA titers; all experienced a sustained response to repeat rituximab therapy. ANCA-titer elevations in four ...