糖尿病心脏自主神经病变(DCAN)是糖尿病常见且严重的并发症。来自国内的研究人员通过靶向P2Y12受体，探究了颈上神经节(SCG)中驻留巨噬细胞与卫星胶质细胞(SGCs)的相互作用机制。研究发现，DCAN大鼠SCG中P2Y12受体、胶质纤维酸性蛋白(GFAP)、巨噬细胞标志物(CSF1R/CSF1 ...
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Research shows clopidogrel as better long-term therapy than aspirin after PCIPeople at high risk for recurrent cardiac events following percutaneous coronary intervention (PCI), a procedure to open ...
P2Y 12 抑制剂与阿司匹林用于冠心病二级预防，前者能降低心梗和出血性中风风险，差异显著。 ### 冠心病治疗现状与研究背景 冠心病（CAD）是全球重大健康问题，其特征为冠状动脉狭窄或阻塞。血小板聚集在动脉粥样硬化血栓形成中起关键作用，抗血小板治疗 ...
微信又改版啦，大家记得点击星标，防止以后找不到我们哦！图 1 急性冠脉综合征的类型和分类。NSTEMI 提示非 ST 段抬高型心肌梗死；STEMI 提示 ST 段抬高型心肌梗死图 3 P2Y12 抑制剂在不需要口服抗凝剂患者中的初始选择。ACS ...
People at high risk for recurrent cardiac events following percutaneous coronary intervention (PCI), a procedure to open blocked arteries, ...
Class, Polyphosphate (polyP)-Based Therapy, Show Promise in Bypassing P2Y12 Inhibition to Restore Normal Clotting Function ...
P2Y12 receptor antagonists (clopidogrel, prasugrel, ticagrelor (Brilinta, AstraZeneca) and ticlopidine) are indicated in all STEMI cases unless urgent surgery is required. Clopidogrel can also be ...
Dual antiplatelet therapy with aspirin plus an oral P2Y12 inhibitor is still indicated for at least 12 months for patients with ACS who are not at high risk for bleeding, and ticagrelor (Brilinta ...
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