为探究衰老细胞中基因组不稳定与炎症的关联，研究人员聚焦 p53，发现其可抑制 CCF 积累及炎症，或为衰老相关疾病治疗提供新靶点。 在生命的长河中，衰老就像一个无法避免的 “关卡”，它带来了身体机能的衰退，还让我们更容易患上各种疾病。随着年龄的 ...

Loss of normal p53 function has been associated with resistance to both chemotherapy and radiotherapy. Introduction of wild-type (wt) p53 by means of adenoviral vectors has been shown to inhibit ...

Researchers found that the loss of p53 function led to the secretion of IL-34 directly. But the blockade of IL-34 restrained ...