Mutations in PDGFB have been associated with meningioma. GMP Human PDGF-BB Protein (GMP-PDBH19) is produced in E. coli cells and consists of amino acids Ser 82 to Thr 190 (Accession # P01127-1).

Human RPE cells become less viable and express VEGF and PDGF when exposed to light; sorafenib and pazopanib decrease both VEGF and PDGF-BB while ranibizumab decreases only VEGF. Sorafenib and ...