X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7 ...

Osteoporosis is common in older adults, especially females and happens due to loss of bone mineral density. Whereas, Paget disease involves thickened and weaker-than-normal bone. The cause is not ...

The disease seems to occur in one of two patterns ... right infraorbital fissure, right maxillary bone, lacrimal bone, malar process and zygomatic bone. These bones were soft, suggesting that ...

Bone cancer can arise in any of the bones of the body but it is most commonly seen in the long bones of the arms and legs. It has the ability to attack the body within the first 20 years of life ...

PRISM (Paget's disease Randomized trial of Intensive versus Symptomatic Management) was a pragmatic randomized controlled trial, designed to compare the effects of intensive bisphosphonate therapy ...

Ipriflavone can block part of the process that leads to bone loss. A bone disease that can cause pain (Paget disease). Early research shows that taking ipriflavone might decrease bone pain in some ...