Cases for whom more than one lobe was lesioned were scored 1 on each of the locations affected (eg, if a patient had a temporoparieto-occipital lesion, he was scored 1 on temporal, 1 on parietal ...

Individual lesion maps were then coregistered ... We found the highest frequency of tubers in frontal lobes and the highest density of tubers in parietal regions. There was significant regional ...