The chemistry of amino acid side chains is critical to protein structure because these side chains can bond with one another to hold a length of protein in a certain shape or conformation.

Proteins are composed of one or more chains of amino acids, which are linked together by peptide bonds and folded into specific three-dimensional structures. Proteins have four levels of structure: ...

Why do problems occur with a special variant of 'protein glues', the split inteins, that severely limit their use in producing proteins? A team has now answered this question.

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Hanson and Stevens 1 recently reported the cocrystal structure of the botulinum neurotoxin B light chain in complex with a 38-residue target peptide of synaptobrevin II. Based on a careful ...

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of amino acids. From stabilizing cell structure to catalyzing chemical reactions, ...

B7-33, a synthetic analog of relaxin-2, has emerged as a focal point in contemporary scientific research due to its selective ...

After translation, the polypeptide is finally folded into the correct shape and becomes a protein. Peptide bonds form between the adjacent amino acids to finalise the structure.