P1 and PAC clones specific for all human subtelomeric chromosome regions 17. We describe here the development of a 12-color FISH assay for telomeric rearrangements (termed M-TEL) using an updated ...
The region shown contains repeat-rich, hypermethylated pericentromeric heterochromatin and an actively transcribed tumour suppressor gene (TSG) associated with a hypomethylated CpG island ...