Gene-silencing techniques, such as antisense-RNA targeting of essential phage-encoded genes (for example, DNA replication) can effectively inhibit the propagation of virulent phages. Trans ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

Huge, bacteria-eating viruses could be a game-changer for antibiotics that currently struggle to fend off deadly infections.

Complementary discoveries have the potential to enhance treatment options for antibiotic-resistant infections. Researchers at ...

The phage therapy market is experiencing significant growth due to the increasing prevalence of antibiotic-resistant infections and the growing interest in alternative treatments. Advances in ...

There is more to learn about bacterial anti-phage defense systems, but this team has already shown that blocking virus replication isn't the only weapon in the bacterial arsenal. In a previous ...