The recovery of phenytoin from mixtures containing different phenytoin formulations and protein mixtures was studied. Three phenytoin solutions (40 mg/µL) were prepared, each in triplicate ...

Marketed formulations of extended phenytoin sodium -- long a difficult medication to titrate because of its unique absorption and saturable elimination pharmacokinetics -- may not be bioequivalent ...

A comparative study of the bioavailability of seven formulations of phenytoin was carried out on 17 patients with epilepsy who were taking phenytoin regularly as part of their drug therapy. Three ...

Phenytoin 50mg/mL; contains alcohol, propylene glycol. Increased cardiovascular risk associated with rapid infusion; monitor during and after therapy; rate reduction or discontinuation may be ...

Introduction Phenytoin is a first-line anticonvulsant used for status epilepticus and neurosurgery prophylaxis. It is highly protein bound (about 90%), primarily to albumin. It has a narrow ...

Alderhey.nhs.uk Introduction Phenytoin has complex pharmacokinetics. The intravenous loading dose of phenytoin for children in status epilepticus has recently been increased from 18 to 20 mg/kg. There ...