The primitive streak—a structure that emerges in mammalian and avian embryos to help assign spatial information to cells during early development—has long been regarded as essential for the genesis of ...

One of the earliest signs of gastrulation in reptiles, birds and mammals (amniotes) is the appearance of a thickening at the midline of the developing embryo, the primitive streak. Here ...

The farnesylation of various proteins, including small G proteins and the nuclear protein Lamin B1, triggers primitive streak formation. Statins inhibit the induction of primitive streak genes by ...