Furthermore, bias may influence the risk estimates. The Heart and Estrogen/Progestin Replacement Study (HERS), published in 1998, was the first large, randomized, controlled trial to evaluate the ...

Estrogen and progesterone combined in OCs act in a synergistic manner in the gonadotropin axis. They decrease the secretion of hypophysial-luteinizing hormone and follicle-stimulating hormone by ...

Minkin says. Others with certain types of migraines, like migraines with aura, shouldn't use combined estrogen and progestin pills, she says. And then there's personal preference. Some people just ...

Low levels of progesterone and estrogen cause the hypothalamus to send a releasing hormone (GnRH) to the pituitary gland. The releasing hormone signals the pituitary gland to release FSH (follicle ...

who had enrolled in the Heart Estrogen/progestin Replacement Study (HERS). HERS was a randomized, placebo-controlled, double-blinded trial that evaluated the effects of HRT in postmenopausal women ...