Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby ...

"There were a number of papers that had suggested a relationship between cell death and oncogenesis, but it was this tie between ced-9 and bcl-2 that really put the nail in the coffin," comments ...

The study is published in Analytical Chemistry. Programmed cell death protein 1 (PD-1) is an important immunosuppressive molecule in the human immune system, and programmed cell death ligand 1 (PD ...

Aligos Therapeutics Inc. has disclosed programmed cell death 1 (PDCD1; PD-1; CD279) and/or PD-1 ligand 1 (PD-L1; CD274) and/or PD-1/PD-L1 interaction inhibitors reported to be useful for the treatment ...

Table 1 In vivo and in vitro approaches to attenuate neurodegeneration in experimental models by targeting programmed cell death Full size table One of the few potential pharmacological approaches ...

There are several programmed cell death pathways that lead to cellular self-destruction, either for developmental processes, tissue maintenance, or stress responses. These include apoptosis, ...

Health Canada has approved MSD's anti-programmed cell death protein 1 (PD-1) therapy Keytruda for treating adults with ...

Researchers identified two anoikis-related genes linked with CTEPH, and that may serve as diagnostic biomarkers or treatment ...