COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase ...

Lancet (in the press). Vane, J.R. Inhibition of prostaglandin synthesis as a mechanism of action for the aspirin-like drugs. Nature New Biol. 231, 232–235 (1971).

Peripheral T-cell lymphoma (PTCL) is an aggressive tumor derived from mature T cells and natural killer cells with an extremely poor prognosis. Ferroptosis is a mechanism of cell death that is ...

Dr. Jason Singh explains that ibuprofen can interfere with prostaglandin synthesis and thermoregulation. As a result, he says ...

More information: Sina Bohnacker et al, A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis, Science Immunology (2024). DOI: 10.1126 ...