(IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein kinase 1; PDK1, 3-phosphoinositide-dependent protein kinase 1; PKB/AKT, protein kinase B ...

D1-receptor signaling cascades can be heterogeneously distributed along cell bodies and dendrites, and A-kinase anchoring proteins (AKAPs) can position phosphatases and kinases in close proximity ...

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

We have reconstituted this process with purified proteins from the budding yeast, Saccharomyces cerevisiae, which has allowed us to define mechanisms involved in origin site selection, origin ...