Peptide bonds are formed by a biochemical ... The chemistry of amino acid side chains is critical to protein structure because these side chains can bond with one another to hold a length of ...

Proteins are the building blocks of life. They consist of folded peptide chains, which in turn are made up of a series of ...

We show here that these diverse peptide sequences bind with comparable affinities to the Numb PTB domain at a common binding site on the surface of the protein. The NMR structure of the Numb PTB ...

Why do problems occur with a special variant of ‘protein glues’, the split inteins, that severely limit their use in ...

FAMU-FSU College of Engineering researchers have created a new method for studying protein degradation within immune cells ...

Proteins are composed of one or more chains of amino acids, which are linked together by peptide bonds and folded into specific three-dimensional structures. Proteins have four levels of structure: ...

While DNA sequencing is routine, determining protein sequences remains one of biology’s toughest challenges, says corresponding author Timothy Jenkins of the Technical University of Denmark. InstaNovo ...

Antimicrobial resistance is a global issue, making the search for a new generation of antibiotics imperative. Scientists ...

the two teams developed the basic structure of the new peptide, predicted its possible interactions with other proteins in heart muscle cells. They used various preclinical molecular, cellular and ...

That process led to the group discovering a lasso peptide that exhibited broad-spectrum antibiotic activity and was effective at killing both gram-positive and gram-negative pathogenic bacteria, along ...