from simple one-component systems to complex multicomponent pathways, with five types of nonhomologous protein secretion system characterized in pathogenic bacteria so far. In the October 3 Cell, Sun ...

Several new targets have been proposed, including proteins essential in the protein secretion pathway such as the type I signal peptidase (SPase), indispensable for the release of the signal ...

By investigating how lipid-soluble Cer is transported between cells, the researchers demonstrated that high-density lipoprotein (HDL) serves as the primary carrier for Cer transport. Upon reaching ...

To maintain homeostasis, intestinal epithelial cells (IECs) must efficiently manage protein production and secretion ...