particularly a family of proteins called APOBEC3 which cause mutations in the HIV virus. Her research and others' show that the virus uses a counterattack that breaks down APOBEC3's defenses ...

In contrast, lentiviruses such as human immunodeficiency virus (HIV) do not depend on host cell ... of lentiviruses is that nucleophilic virion proteins chaperone viral nucleic acids across ...

For the first time, the treatments would be aimed not at the virus itself ... A compound that blocks the CCR-5 protein might prevent HIV infection as if a person had naturally inherited the ...

HIV is a virus. Viruses are microscopic germs that are unable to multiply (replicate) by themselves. Instead, they need to find and infect a cell that will act as a host in which new viruses can be ...

Nef protein, which is expressed by HIV during infection, shields the virus from immune detection. This protein reduces a molecule on the surface of the cell that acts as a marker to help the ...

The cell that the vector later invades will then produce proteins created by the virus. The vectors and copied ... You have just produced a naked-DNA HIV vaccine. Trials for a genetic vaccine ...

Many vaccines work by introducing a protein to the body that resembles ... (EMPEM), lets the researchers see exactly where on ...

LEN represents a novel class of HIV therapies by targeting ... LEN binds directly to the capsid protein, disrupting several critical steps in the virus’s life cycle. Figure 1.

To enter other cells, HIV’s protein envelope must go through multiple glycosylation events, adding sugar moieties to the viral surface while in the infected cell. Therefore, the researchers came up ...