Proteolysis is the enzymatic process by which proteins are degraded into their component polypeptide or amino acid parts. This generally occurs through protease-mediated hydrolysis of peptide ...
X.D. Wang, R. Sato, M.S. Brown, X.X. Hua, J.L. Goldstein, "Srebp-1, a membrane-bound transcription factor released by sterol-regulated proteolysis," Cell, 77:53-62, 1994. (Cited in more than 65 ...
In a recent study published in the journal Nature, researchers from the United States of America developed the synthetic intramembrane proteolysis receptor (SNIPR) architecture to activate ...