Nucleoside phosphorylases are enzymes ... This innovative approach opens up new avenues for exploring purine and triphosphate analogues, potentially leading to more effective therapeutic agents.

Imbalances in pyrimidine biosynthesis can lead to various disorders, such as orotic aciduria and pyrimidine nucleoside phosphorylase deficiency. Some pyrimidine analogs, such as azidothymidine (AZT) ...