In fact, rRNA is sometimes called a ribozyme or catalytic RNA to reflect this function. Eukaryotic and prokaryotic ribosomes are different from each other as a result of divergent evolution.

This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule with enzymatic properties. The catalytic center of the ribosome, known as the peptidyl transferase center (PTC), is ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Transfer RNA (tRNA) molecules are responsible for delivering amino acids to the ribosomes during protein synthesis. Each tRNA molecule has an anticodon that is complementary to a specific codon on the ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

This effect, which they termed ribosome cooperativity, extended to delays in other difficult mRNA regions, such as translation through repetitive sequences and complicated RNA structures. “This allows ...

View Full Profile. Learn about our Editorial Policies. Further investigation into SNORA13 revealed that it modifies RNA bases in the ribosome’s active site, suggesting that this small RNA may affect ...

The research field of "cellular IRESes" lay dormant for decades, as there was no uniform standard of reliable methods for the ...

A visualization of this process shows ribosomes becoming brighter as they actively translate RNA. The team has already uncovered new insights using this approach. “We observed that individual ...