发育和衰老贯穿人类一生，伴随着免疫系统的逐渐成熟和不可避免的退化。出生后，免疫系统逐渐成熟，能够更好地抵御外来病原体。相反，免疫老化导致感染、心血管疾病和癌症的发病率更高。此外，最近有报道称，老化的免疫细胞会导致心脏和肝脏等实体器官的老化，这可能是全 ...

Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...

Recent breakthroughs in single-cell RNA sequencing (scRNA), such as the recently developed "RevGel-seq" method, have revolutionized plant cell analysis. This technique, independent of special ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

Five stages of single-cell sequencing (sc-seq) experimental workflow. (A) Dissociation of the desired tissue into a cellular suspension is the first step in the sc-seq experimental workflow. (B–C) ...

Single-cell sequencing applications have accelerated breakthroughs in life sciences, leading to significant impacts for disease treatments. Single-nuclei RNA-sequencing (snRNA-Seq) has been shown to ...