发育和衰老贯穿人类一生，伴随着免疫系统的逐渐成熟和不可避免的退化。出生后，免疫系统逐渐成熟，能够更好地抵御外来病原体。相反，免疫老化导致感染、心血管疾病和癌症的发病率更高。此外，最近有报道称，老化的免疫细胞会导致心脏和肝脏等实体器官的老化，这可能是全 ...

Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...

Recent breakthroughs in single-cell RNA sequencing (scRNA), such as the recently developed "RevGel-seq" method, have revolutionized plant cell analysis. This technique, independent of special ...

In recent years, scientific advancements have transformed our understanding of diseases, particularly at the cellular level.

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

Five stages of single-cell sequencing (sc-seq) experimental workflow. (A) Dissociation of the desired tissue into a cellular suspension is the first step in the sc-seq experimental workflow. (B–C) ...

Single-cell sequencing applications have accelerated breakthroughs in life sciences, leading to significant impacts for disease treatments. Single-nuclei RNA-sequencing (snRNA-Seq) has been shown to ...