2018 saw a breakthrough in the field of RNA interference (RNAi), when the US FDA approved the first drug using this gene-silencing mechanism. Five years and five more approved drugs later, RNAi ...

The results of this work reveal how an alternative splicing mechanism regulates an essential factor for neuronal identity.

This discovery laid the foundation for understanding the RNAi mechanism and its potential applications. Fire and Mello were awarded the Nobel Prize in Physiology or Medicine in 2006 for their work on ...

Arrowhead Pharmaceuticals, Inc. shines with 19 clinical programs, strategic partnerships, and promising RNAi data. Click for ...

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced presentation of preclinical data supporting the advancement of two first-in-class clini ...

We believe the exquisite specificity afforded by the RNAi mechanism of action and our industry-leading, proprietary GalNAc-conjugate approach for delivery to the liver is an unparalleled ...

Rzs and Dz are also being explored as additional mechanisms for gene silencing in many viruses including influenza and have shown their potential in controlling these viruses. Although ...