Calcium hydroxylapatite (CaHA) fillers, such as Radiesse, have become increasingly popular in aesthetic medicine for their ability to restore volume and stimulate collagen production in the skin.

Mayer et al. examined the safety and effectiveness of calcium hydroxylapatite, a novel bulking agent, and compared it to bovine collagen, the FDA standard agent. This prospective, single-blind ...

Calcium hydroxylapatite-induced skin necrosis occurred in 2 patients after injection in the glabella and the nasolabial fold, respectively. Supportive treatment with oral steroids, nitroglycerin ...