Mendelian randomization (MR) is a relatively new form of evidence synthesis and causal inference that is of growing importance in observational epidemiology. The approach can be viewed as an ...

Introduction to Mendelian randomization, the problems with using traditional observational studies to investigate causality, and Randomized controlled trials as the gold standard for causal research.

This innovative programme aims to extend the now widely utilized Mendelian Randomization (MR) paradigm in ways that will substantially increase its utility in population and clinical sciences. The ...

The following is a summary of “Mendelian randomization of plasma proteomics identifies novel ALS-associated proteins and their GO enrichment and KEGG pathway analyses,” published in the March 2025 ...

Researchers from the HIV Prevention Trials Network (HPTN) presented results from the HPTN 094 ("INTEGRA") study at the 2025 ...

Aortic dissection is a life-threatening condition with complex immunological underpinnings. This article explored the causal relationships among immune cells, inflammatory proteins, and aortic ...