Researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences and the Shanghai Institute of Organic Chemistry have divulged EGFR (L858R/T790M/C797S triple mutant) and ...

and the use of dominant-inhibitory Ras mutants has contributed greatly to this accomplishment. In over 600 reports published so far, dominant-inhibitory Ras has been used to suppress the ...

Accordingly, the researchers next plan to investigate the extent to which individual KRAS mutations influence response to EGFR inhibitors, such as cetuximab. “Future personalized patient ...