Inhibition of the renin-angiotensin system (RAS) has been shown to decrease mortality and morbidity in patients with heart failure and postmyocardial infarction. Experimental and clinical data ...

The effective blockade of angiotensin II effects may therefore ... These mechanisms demonstrate the pivotal role of the RAS and are believed to be major determinants in left ventricular remodeling ...

Although most of the medical cognoscenti had reservations concerning the role of the renin–angiotensin system in human hypertension, I, along with Vane and a few other key individuals at Squibb ...

ONTARGET showed that dual renin–angiotensin system blockade prevents microalbuminuria but facilitates transient renal function impairment in nonproteinuric patients with atherosclerotic vascular ...

BACKGROUND: Limited evidence exists on the prognostic role of continuing medical therapy in patients with heart failure (HF) and an ejection fraction (EF) that has improved over time. This study ...

was looking at gene expression data from the lung fluid of COVID-19 patients on his computer screen when he spotted something striking—the expression of genes for key enzymes in the renin-angiotensin ...

Patients who have been treated for heart failure and experience an improvement in their pump function are still at higher ...

We have a longstanding interest in the role of the renin-angiotensin system (RAS) in AD. Our work has helped characterise and better understand the genetic, biochemical and pathological role of brain ...

Laura undertook a part-time PhD between January 2006 and July 2014. Her PhD was sponsored by the charity BRACE and focused on the Renin Angiotensin System (RAS) which is an important enzyme pathway ...

Patients who have been treated for heart failure and experience an improvement of their pump function, are still at higher risk of heart-related death or hospitalization if they stop taking heart ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at ...