The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

should ultimately elucidate the molecular mechanisms of receptor activation. These problems will be challenging and may well necessitate solving structures of receptors in complex with their ...

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid mediators exert their effects by activating two G protein-coupled receptors, ...

Music can evoke intense pleasure, sometimes experienced physically as pleasant "chills." While the effect of music on ...

A new imaging study showed that listening to favorite music affects the function of the brain's opioid system.

"The challenge, however, is to limit their effects to astrocytes, because strong and prolonged activation of the same ...

"What we found was that the chemicals were not able to activate the mosquito wasabi receptor as effectively when temperatures exceeded the heat activation threshold," said Piermarini. "So the ...