We are also actively investigating the regulation of Syk tyrosine kinase binding to membrane immune receptors and other signaling proteins. Syk recognizes doubly phosphorylated regions of the receptor ...

signaling array. Specific goals include elucidation of the mechanisms by which attractant and adaptation signals are transmitted through the transmembrane receptors to the kinase, and how these ...

Gao Guo is an assistant professor in the UAB Department of Neurosurgery. His research focuses on elucidating the role of receptor tyrosine kinase in the invasion and survival of glioblastoma (GBM). He ...

The FDA has granted Priority Review to nipocalimab for the treatment of antibody positive patients with generalized myasthenia gravis.

TIE1, a receptor tyrosine kinase, was found to be upregulated by ... In conclusion, this work has identified a novel signaling pathway involving ING5, TIE1, and PDK1 Y163 phosphorylation that ...