An LT-scFv antibody fragment specific for sheep red blood cells was incorporated into the membrane of the Daudi B cell line. Cells were washed and subsequently mixed with sheep red blood cells in ...
Haemolytic disease of the fetus and newborn (HDFN) occurs when there is transplacental passage of maternal immunoglobulin G ...
Delayed transfusion reactions are: (i) hemolytic, caused by anamestic responses to red cell antigens ... These include white cell antibody-mediated transfusion-related acute lung injury (TRALI ...
To do this, scientists typically integrate the genes encoding the relevant antibody’s subunits, called the heavy and light chain, into a host cell line. Those with the best yields are grown ...
In this event, the plasma, which is usually group O transfused to A, B or AB recipients, may contain sufficient potent antibodies directed against A or B antigens on the recipient's red cells to ...
Known as the 'man with the golden arm', James Harrison's blood contained a rare antibody that saved millions of lives.
Contrary to what you likely learned in school, ferrying oxygen isn’t the only function of red blood cells. In a study published today (October 20) in Science Translational Medicine, researchers show ...
Constant Regions (Fc): The constant regions form the stem of the Y-shaped molecule and determine the antibody's effector functions, such as complement activation and binding to immune cell receptors.
In the cell-binding assay, CD47 antibodies bound to tumor cells (Jurkat cells) but only weakly bound to CD47 on the surfaces of the red blood cells at high concentrations. These results were ...
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