and some other kidney cell types, can take on a whole new job: producing renin, a substance typically manufactured in specialized cells in the kidneys to help maintain blood pressure. Scientists ...

Physiologic conditions are important modifiers of renin activity. These include body posture, dietary salt intake, diurnal variation, age, race, renal disease, and confounding medications. As renin ...

The human kidney displays a tubular immaturity at birth ... in the zona glomerulosa of the adrenal gland, secondary to renin stimulation via angiotensin II and to potassium stimulation (4).

Regulation of blood pressure: Kidneys produce renin, an enzyme that helps regulate blood pressure. Electrolyte balance: They maintain the balance of electrolytes such as sodium, potassium ...

One patient progressed to end-stage renal disease within 1 month of biopsy. The other seven patients received renin–angiotensin system blockade and were encouraged to discontinue anabolic ...

Edgar Lerma, MD, provides insights into the pathophysiology of IgA nephropathy (IgAN) and the therapeutic promise of ...

Palatin Technologies, Inc. (NYSE American: PTN), a biopharmaceutical company developing first-in-class medicines based on ...

The U.S. Food and Drug Administration (FDA) on Wednesday granted accelerated approval for Novartis AG’s (NYSE:NVS) Vanrafia ...

Novartis’ Vanrafia (atrasentan) has been granted accelerated approval by the US Food and Drug Administration (FDA) to treat ...

Vanrafia reduces proteinuria in adults with primary immunoglobulin A nephropathy (IgAN). It has a wholesale acquisition cost ...