We also constructed a ‘super-enhancer’ vector (AV.SupEnh), which ... Figure 4: Intermolecular cis activation increases rAAV-mediated reporter gene expression in muscle in vivo.
CREs, including enhancers and promoters, are essential for controlling when and where genes are turned on or ... lentivirus-based massively parallel reporter assay (lentiMPRA), which the authors ...
RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...