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代谢重编程:揭开 Richter 综合征转化的代谢特征与治疗新契机
为探究 Richter 综合征(RS)代谢特征,研究人员利用患者来源的肿瘤异种移植模型及细胞系开展研究。结果表明 RS 细胞存在代谢重编程,依赖葡萄糖和谷氨酰胺代谢。这为 RS 治疗提供新方向,有望开发针对性疗法。
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