Researchers identified three new all-oral drug regimens that include at least one of two new drugs for treatment of ...

The advent of new drugs to treat tuberculosis and enhanced funding now permit randomized, controlled trials of shortened-duration, all-oral treatments for rifampin-resistant tuberculosis.

Barbiturates, hydantoins, rifampin, other hepatic enyzme inducers ... aspirin in hypoprothrombinemia. Potentiated by oral contraceptives. Monitor oral anticoagulants.

Three all-oral shortened regimens have noninferior efficacy compared with standard therapy for fluoroquinolone-suscep ...

Prednisolone (as sodium phosphate) 15mg/5mL; contains alcohol, benzoic acid; wild-cherry flavor. Systemic fungal infections, cerebral malaria, optic neuritis: not recommended. Tuberculosis.

"For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis," they wrote. "These findings support the use of three new, all-oral ...

The new regimens, discovered through the endTB clinical trial, offer promising solutions for people suffering from TB resistant to rifampin, a strain that has become increasingly difficult to treat.

Rifampin-resistant tuberculosis has traditionally been treated with 18-to-24-month regimens, but shorter, all-oral regimens may offer efficacious alternatives. New research findings are summarized ...