For example, clozapine remains the most effective treatment for treatment-resistant schizophrenia, even though its putative mechanism of action, blockade of 5HT2a and D2 receptors, has been ...

These results could help to decipher dysfunctions in the neural and computational mechanisms of schizophrenia. Furthermore, ...

Bristol Myers Squibb clocked $10 million in sales for new schizophrenia drug Cobenfy in the fourth quarter of 2024, with the ...

Schizophrenia is thought to involve a dysfunction ... Now ketamine, a glutamatergic NMDA receptor antagonist, may provide a mechanism that could link these pathways. Figure 1: A schematic of ...

"We are overdue for a medication that targets schizophrenia with a different mechanism of action," Kunovac told ABC News. The ...

If this is the case, knowing more about these alterations could help researchers understand the biological mechanisms behind the disorder. In addition to schizophrenia, retinal alterations have ...

Karuna Therapeutics said this morning that the FDA has formally started its review of KarXT, aiming to become the first drug to reach the market for schizophrenia with a new mechanism of action in ...

If this is the case, knowing more about these alterations could help researchers understand the biological mechanisms behind the disorder. In addition to schizophrenia, retinal alterations have ...

The M1/M4 muscarinic receptor agonist is vying to be the first drug to reach the market for schizophrenia with a new mechanism of action in decades. It is also in phase 3 clinical testing as an ...