Differential epitope tagging of the receptor cDNA followed by selective immunoprecipitation of the dimer has been used to confirm the ability of members of the rhodopsin, secretin, and calcium ...
“When Heptares formed, we chose to focus on GPCRs because we knew that targeting these receptors leads to drugs ... the largest), secretin and adhesion (both class B), glutamate (class ...
Secretin receptors have been identified in the pancreas, stomach, liver, colon and other tissues. When secretin binds to secretin receptors on pancreatic duct cells it opens CFTR channels ...