This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...

With clinical trials results trickling in, “antiaging” drugs that clear away senescent cells are proving to be promising — ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and ...

New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

requiring constant and precise regulation of intestinal stem cells (ISCs) to sustain the production of new absorptive enterocytes and secretory cells, including Paneth, goblet, tuft, and ...