Hyponatremia is a serum sodium concentration ... A value of less than 120 mEq/L is considered a critical value requiring immediate intervention (Larsen, Kronenberg, Melmed, & Polonsky, 2003 ...

The investigators subsequently monitored the long-term effects of dose-adjusted satavaptan treatment in the same group of patients with SIADH. Ten patients completed the 12-month open-label study ...