Sickle cell conditions are genetic blood disorders that affect haemoglobin, the molecule in red blood cells responsible for ...

The Food and Drug Administration has approved the world’s first medicine based on CRISPR gene-editing technology, a ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

Over 300 abnormal hemoglobins — such as sickle cell hemoglobin — have been discovered, most of which are either neutral or harmful to their carriers, and numerous thalassemias, which result ...

In the UK, approximately 17,500 people have sickle cell disease and 300 babies are born with the condition each year. It is a genetic disorder caused by inherited mutations in a person's DNA that ...

Bluebird Bio and Xcellbio have entered into an agreement to support the commercialization of sickle cell gene therapy ...

Mutations are the only source of new alleles ... allele in their body cells then they will have the genetic condition sickle cell anaemia. The sickle shaped red blood cells can block blood ...

Groundbreaking gene-editing treatment exa-cel is now available for NHS patients with sickle cell disease, offering a ...

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ... Brains of People With ...

The potential target, the FLT1 gene, contributes to the production of a protein, fetal hemoglobin, whose presence is already known to improve the lifespan of people with sickle cell disease.