In addition, he studies the spindle assembly checkpoint which ensures proper chromosome segregation and is often deregulated in cancer. Joan Massagué, PhD Joan Massagué studies the control of stem ...

Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during ...

These spindle microtubules are responsible for ... Yet, to form correct attachments, they must remain closely connected. In cancer cells, however, we often observe that subdomains uncouple ...