because aligning expressed sequences of different splice variants of the same gene usually results in a typical gapped pattern of alignment. The recent information explosion in nucleotide ...

Oxford, UK and San Jose, California, 9 January 2024 - (OBT), a clinical stage oncology company with a pipeline of ...

or the alternative inclusion or exclusion of exons (splice variant). There are 1,815 genes for which biallelic pLoF variants (where both copies of a gene are likely to be inactive) are found in at ...

Researchers from AUTOTAC Bio Inc. and affiliated organizations presented preclinical data for ATC-324, a novel autophagy-targeting chimera (AUTOTAC) designed to induce androgen receptor (AR) ...

Defective splicing variants might also play a role in the development of neurodegenerative diseases like Alzheimer's or Parkinson's. On the other hand, this mechanism may be targeted by new ...

Defective splicing variants might also play a role in the development of neurodegenerative diseases like Alzheimer’s or Parkinson’s. On the other hand, this mechanism may be targeted by new ...