right)\) Look at the diagram and imagine going from X to Z. How would you write the path in vectors using only the vectors \(\overrightarrow {XY}\) and \(\overrightarrow {ZY}\)? You could say it ...

Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...

Figure 1: Strategy for packaging a large gene by the split AAV vectors through heterodimerization. Figure 3: Characterization of the split AAV vector heterodimerization by RT–PCR and DNA-PCR.

They can infect both dividing and non-dividing cells and provide high levels of gene expression. However, adenoviral vectors can trigger strong immune responses, limiting their long-term efficacy.

lentivirus-based vectors, derived from the HIV-1 retrovirus, are of growing interest in gene and cell therapy, particularly in immuno-oncology, due to their ability to infect dividing and ...