How rigorous are the criteria used to conclude that complete differentiation of organ-specific stem cells to a heterologous lineage has occurred? For the most part, the lineage-unrelated progeny ...

Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...