Unrelated human MSCs did not elicit T-cell activation in vitro and suppressed T-cell activation by Tuberculin and unrelated allogeneic lymphocytes in a dose-dependent manner. Cell-free MSC culture ...

and activation of HLA-B-restricted T cells, thereby serving clues for T1D onset. TRIM28 is known to recruit chromatin modifiers to its target regions to co-regulate gene expression in multiple ...

T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for ...

New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte ...

More information: Hongxing Shen et al, HIF1α-regulated glycolysis promotes activation-induced cell death and IFN-γ induction in hypoxic T cells, Nature Communications (2024). DOI: 10.1038 ...

Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular proteins, such as those from bacteria, in order to activate an ...

The following is a summary of “FC03 T17 polarization of skin-homing (CLA-positive) T cells is maintained by ...

The direct-to-cell Starlink system in Southern California will deliver wireless emergency alerts and power SMS texting to 911 ...

Novel programs will combine validated cell-targeted LNP (ctLNP) delivery with siRNA to selectively modulate T cells in vivo Programs to focus on silencing hard-to-drug targets of high therapeutic ...

Back in October, when Hurricane Milton devastated Florida, T-Mobile and Starlink enabled their satellite-based texting ...