Tolerogenic dendritic cells in the intestines are shown to reduce the immune responses caused by exposure to food proteins.

Projects in the laboratory focus on a range of specific processes that relate to; 1) maintenance and function of the marginal zone in the spleen and responses to blood borne pathogens, 2) initiation ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies ...

A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...

The immune system must be able to rapidly target invaders such as viruses while avoiding innocuous stimuli, or allergies may develop.

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

comp Shih et al. compared T cell-dependent immune responses to the hapten 4-hydroxyl-3-nitrophenyl acetyl (NP) in mice that carry targeted V H B1-8 antibody genes with high or low antigen-binding ...