1 Similarly, as TREM2 becomes a key therapeutic target, researchers will seek new ways to detect and alter the receptor pathway. Finally, the full range of potential ligands for TREM2—and their ...

In cases where clearance was limited, phagocytosis-promoting genes, including TREM2, A2M, and LAMP1 were more strongly dialed up, while complement and unfolded protein response pathways were turned ...