Corticobasal degeneration (CBD) is characterized by either ... may also have variable underlying pathology. The human tau gene is located over 100 kb on the long arm of chromosome 17q21; it ...

Even tau-related cases of FTLD ... Table 1 Overview of the features of corticobasal degeneration, progressive supranuclear palsy, and the three subtypes of frontotemporal lobar degeneration ...

This group has now shown that a low ratio of these tau forms reliably differentiates ... (44 with frontotemporal dementia, 20 with corticobasal degeneration syndrome, 29 with Alzheimer disease ...

and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain. A team of researchers led by UC Santa Barbara scientists has found potential ways ...

The term corticobasal degeneration is reserved for autopsy-confirmed CBS. The cause of CBS is not yet known. Like other neurodegenerative diseases, patients with CBS accumulate misfolded proteins ...

Notably, there are currently no approved therapies that target pathological tau. In mice ... frontotemporal lobar degeneration, progressive supranuclear palsy, corticobasal degeneration, and ...