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生物通
11 天
HIV 治疗新发现:富马酸替诺福韦酯与丙酚替诺福韦对代谢参数影响大 ...
在一线 ART 药物中,丙酚替诺福韦(Tenofovir Alafenamide,TAF)和富马酸替诺福韦酯(Tenofovir Disoproxil Fumarate,TDF)是常用的核苷或核苷酸逆转录酶抑制剂。虽然它们在抑制 HIV RNA 方面疗效相当,且 TAF 对肾功能和骨矿物质密度的不良影响更小,但近年来有研究指出 ...
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