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The RNA world hypothesis gains support from the in vitro evolution of a bifunctional ribozyme that can recognize an activated glutaminyl ester and subsequently aminoacylate a tRNA molecule.

“Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA,” PNAS, 115:13318–23, 2018. Proponents of the RNA world theory argue that life on Earth originated from ...

“It’s definitely a key advance in the field of understanding what RNA polymerase ribozymes can do, and it has pretty important implications for the RNA world theory,” he added. Study coauthors Gerald ...